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This page is not in the website's main menu and is only available via direct link. It's an early collection of information specific to Acute Myeloid Leukemia (AML) that I am researching for a friend in need (👋)
The content may change as I learn and add more. Going to do a chronological approach to keep the newest stuff at the top.
Dec. 7
ULKAMLAVEN
Therapy of Acute Myeloid Leukemia using azaCITIDine and Venetoclax
[ULKAMLAVEN Protocol](http://www.bccancer.bc.ca/chemotherapy-protocols-site/Documents/Leukemia-BMT/ULKAMLAVEN_Protocol.pdf)
# Dec. 6
Seems sub-types aren't as relevant in this situation, but understanding what the treatment drugs will be will be useful. Here is a link to the page of common treatments BCCA prescribes for AML:
[Leukemia related treatments (BCCA)](http://www.bccancer.bc.ca/health-professionals/clinical-resources/chemotherapy-protocols/leukemia-bone-marrow-transplant#Leukemia)
# Nov. 26
Here are a few first links to articles I've read so far:
This one provides a very basic overview of blood cells and leukemia, and introduces AML:
[What Is Acute Myeloid Leukemia (AML)? | What Is AML? | American Cancer Society](https://www.cancer.org/cancer/types/acute-myeloid-leukemia/about/what-is-aml.html)
# Treatment
Seems the main treatment for AML is [Chemotherapy](3.%20Treatments/3.6%20%20Standard%20care/Chemotherapy.md). In some cases [Radiation therapy](3.%20Treatments/3.6%20%20Standard%20care/Radiation%20therapy.md), and surgery or bone marrow transplants.
Here is a decent overview article on chemotherapy in general:
[Chemotherapy | Canadian Cancer Society](https://cancer.ca/en/treatments/treatment-types/chemotherapy)
And this one is specific to AML chemo:
[Chemotherapy for acute myeloid leukemia | Canadian Cancer Society](https://cancer.ca/en/cancer-information/cancer-types/acute-myeloid-leukemia-aml/treatment/chemotherapy)
# Side effects
The potential chemo drugs on the list were all new to me, so I'm not sure what the specific side effects are. But I'm assuming there will be many common ones to the chemo I did, so hopefully some of the things I researched and found helpful might be of use here too.
Once the sub-type is known, the likely chemo drugs will be identifiable, and then researching what to expect and how to reduce those side effects.
Edit: subtypes don't seem to be of relevance at this time, dropping this section to the bottom.
~~This one gets into the differences in the various sub-types of AML. It sounds like treatment strategies can vary depending on the sub-type, so until that is known (end of month, right?) it's hard to dig too far.
[Acute Myeloid Leukemia (AML) Subtypes and Prognostic Factors | American Cancer Society](https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/how-classified.html)
Here is the chart from that site with main sub-types:~~
| | |
|---|---|
|**FAB subtype**|**Name**|
|M0|Undifferentiated acute myeloblastic leukemia|
|M1|Acute myeloblastic leukemia with minimal maturation|
|M2|Acute myeloblastic leukemia with maturation|
|M3|Acute promyelocytic leukemia (APL)|
|M4|Acute myelomonocytic leukemia|
|M4 eos|Acute myelomonocytic leukemia with eosinophilia|
|M5|Acute monocytic leukemia|
|M6|Acute erythroid leukemia|
|M7|Acute megakaryoblastic leukemia|