A sister extract to AHCC also from the shiitake mushroom. Sounds really interesting in its effects on cancer. Not as easy to source as AHCC, but it's out there. The wiki page cites a bunch of human trials happening in Japan (no surprise given their adoption of AHCC in clinical settings), but of course uncertain efficacy and results so far. Question of whether oral administration works, suggestion it must be done intravenously. [Lentinan - Wikipedia](https://en.wikipedia.org/wiki/Lentinan) This is a page from a commercial supplement provider, they've got links to a bunch of papers thought which is useful in reading up: [Lentinan AXT - Zenius Labs - Zenius Labs](https://zenius-labs.com/lentinan-axt/) Another, less interesting: [Aloha Medicinals – Pure Shiitake – Certified Organic Mushrooms – Lentinula Edodes – Health Supplement – Supports Cardiovascular, Skin and Brain Function 525mg – 90 Vegetarian Capsule (3-Pack) – LifeIRL](https://lifeirl.com/products/aloha-medicinals-pure-shiitake-certified-organic-mushrooms-lentinula-edodes-health-supplement-supports-cardiovascular-skin-and-brain-function-525mg-90-vegetarian-c-2/)