Chromium picolinate Chromium is an essential mineral that appears to have a beneficial role in the regulation of insulin action and its effects on carbohydrate, protein and lipid metabolism. Chromium is an important factor for enhancing insulin activity. Chromium picolinate, specifically, has been shown to reduce insulin resistance and to help reduce the risk of cardiovascular disease and type 2 diabetes. Source: [A scientific review: the role of chromium in insulin resistance - PubMed](https://pubmed.ncbi.nlm.nih.gov/15208835/)