[Boswellia (boswellic acid)](https://www.mskcc.org/cancer-care/integrative-medicine/herbs/boswellia) >Colorectal cancer (CRC) is a complex disease with genetic and epigenetic alterations in many key oncogenes and tumor suppressor genes. The active principle of a gum resin from Boswellia serrata, 3-acetyl-11-keto-β-boswellic acid (AKBA), has recently gained attention as a chemopreventive compound due to its ability to target key oncogenic proteins such as 5-lipoxygenase and nuclear factor-kappaB. AKBA has been shown to inhibit the growth of CRC cells; however, the precise molecular mechanisms underlying its anticancer activities in CRC remain unclear. >Source: [Boswellic acid exerts antitumor effects in colorectal cancer cells - PMC](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510738/) Food with it is important: >The presence of food in the stomach, as well as the type of food eaten, dramatically alters the bioavailability of boswellic acids, and bile acids significantly affect their absorption. When human subjects ingested boswellic acids along with a high-fat meal, the areas under the plasma concentration-time curves and peak concentrations totaled several times higher than when the herbal preparations are taken in the fasting condition. >Source: [Boswellic Acid - an overview | ScienceDirect](https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/boswellic-acid)