[Berberine](https://www.mskcc.org/cancer-care/integrative-medicine/herbs/berberine) This one seems to hit all three metabolic pathways, and is very safe to use. Promotes apoptosis in cancer cells. #paper [Berberine versus placebo for the prevention of recurrence of colorectal adenoma: - PubMed](https://pubmed.ncbi.nlm.nih.gov/31926918/) [Berberine Promotes Apoptosis of Colorectal Cancer](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357823/) Dosage: 300-500 mg, three times daily