[6-Gingerol (Ginger)](https://www.mskcc.org/cancer-care/integrative-medicine/herbs/ginger) >Inhibits the metastasis of MDA-MB-231 breast cancer cells and induced apoptosis in LNCaP prostate cancer cells inhibits the growth of several types of murine tumors such as melanomas, renal cell carcinomas, and colon carcinomas by enhancing the infiltrations of tumor-infiltrating lymphocytes CD4 and CD8 T-cells and B220+ B-cells. > >A few studies have been published on the anticancer properties of [6]-gingerol and its mechanism of action against colon cancer. >Radhakrishnan _et al._ reported the inhibition of ERK1/2/JNK/AP-1 pathway as a possible mechanism behind the anticancer as well as chemopreventive efficacy of [6]-gingerol against colon cancer [83,86]. In the case of human breast cancer, the combination chemotherapeutic protocol, [cyclophosphamide](https://www.sciencedirect.com/topics/chemistry/cyclophosphamide "Learn more about Cyclophosphamide from ScienceDirect's AI-generated Topic Pages"), [doxorubicin](https://www.sciencedirect.com/topics/chemistry/doxorubicin "Learn more about Doxorubicin from ScienceDirect's AI-generated Topic Pages"), and [5-fluorouracil](https://www.sciencedirect.com/topics/chemistry/5-fluorouracil "Learn more about 5-Fluorouracil from ScienceDirect's AI-generated Topic Pages") [6]-gingerol showed the highest anticancer potency that is superior to that of the combination protocol in the breast cancer cell model, MCF-7. >Source: [6-Shogaol - an overview | ScienceDirect Topics](https://www.sciencedirect.com/topics/chemistry/6-shogaol)